Both Melatonin Sleep and Amitriptyline offer similar effectiveness, with differences in speed and duration of relief.

Melatonin Sleep has fewer side effects and is less likely to interact with other medications.

Amitriptyline has a more stable effect and is less likely to lead to addiction over time.

Melatonin Sleep has a simple once-daily dose, making it easier to stick to a treatment routine.

Both drugs have some contraindications depending on individual health conditions, but neither has major restrictions.

Both drugs are good options depending on the patient’s needs, with Melatonin Sleep better for quick relief and Amitriptyline for long-term management.