Both Estazolam and Amitriptyline offer similar effectiveness, with differences in speed and duration of relief.

Estazolam has fewer side effects and is less likely to interact with other medications.

Amitriptyline has a more stable effect and is less likely to lead to addiction over time.

Estazolam has a simple once-daily dose, making it easier to stick to a treatment routine.

Amitriptyline is safer for patients with cardiovascular issues or diabetes.

Both drugs are good options depending on the patient’s needs, with Estazolam better for quick relief and Amitriptyline for long-term management.