Both Abilify Maintena and Amitriptyline offer similar effectiveness, with differences in speed and duration of relief.

Abilify Maintena has fewer side effects and is less likely to interact with other medications.

Amitriptyline has a more stable effect and is less likely to lead to addiction over time.

Abilify Maintena has a simple once-daily dose, making it easier to stick to a treatment routine.

Both drugs have some contraindications depending on individual health conditions, but neither has major restrictions.

Both drugs are good options depending on the patient’s needs, with Abilify Maintena better for quick relief and Amitriptyline for long-term management.