Indomethacin

From 10.23$

Active Ingredients

indomethacin (oral)

Drug Classes

Nonsteroidal anti-inflammatory drugs

Scoring is done by our AI based assistant on the data from the FDA and other sources

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Contraindications

Indomethacin for Patent Ductus Arteriosus

What is Patent Ductus Arteriosus?

Patent Ductus Arteriosus (PDA) is a heart condition that affects newborn babies. In a normal heart, a ductus arteriosus is a blood vessel that connects the pulmonary artery to the aorta. It allows blood to bypass the lungs and go directly to the body. However, in babies with PDA, this blood vessel fails to close after birth, causing excess blood to flow to the lungs and leading to various complications.

Treatment with Indomethacin

Indomethacin is a medication that is often used to treat PDA in newborn babies. It works by inhibiting the production of prostaglandins, which are hormone-like substances that help to keep the ductus arteriosus open. By reducing prostaglandin levels, Indomethacin helps to close the ductus arteriosus, allowing the heart to function normally. Indomethacin is typically administered orally or through an IV, and its effects are usually seen within a few days of treatment.

How Effective is Indomethacin for PDA?

Studies have shown that Indomethacin is highly effective in closing the ductus arteriosus in babies with PDA. In fact, it is considered the first-line treatment for this condition. When used correctly, Indomethacin has been shown to close the ductus arteriosus in up to 90% of cases. This can lead to significant improvements in the baby’s overall health and well-being, including reduced symptoms of heart failure and improved feeding and growth.

Indomethacin Dosage for Patent Ductus Arteriosus Treatment

Indomethacin Treatment for PDA

Indomethacin is a medication commonly used to treat Patent Ductus Arteriosus (PDA) in infants. PDA is a condition where the ductus arteriosus, a blood vessel that connects the pulmonary artery to the aorta, fails to close after birth.

Determining the Right Indomethacin Dose

The dose of indomethacin for PDA treatment is typically determined by the infant’s weight. The standard dose is 2-3 mg/kg, given orally or rectally, every 12 hours for a total of 3-4 doses. However, the dose may need to be adjusted based on the infant’s response to treatment.

Monitoring the Effectiveness of Indomethacin Dosage

It is essential to monitor the effectiveness of the indomethacin dosage by regularly checking the infant’s blood pressure and heart rate. The goal of treatment is to close the PDA, which can be confirmed through echocardiography or other imaging tests. If the PDA does not close after the initial dose, the dose may need to be increased or the treatment duration extended. In some cases, a second course of indomethacin may be necessary to achieve closure of the PDA.

After being prescribed Indomethacin for my Patent Ductus Arteriosus, I was a bit skeptical about how well it would work. However, I was pleasantly surprised to find that the medication started working within a few days of taking the recommended dose of 2.5 mg/kg/day. The side effects were minimal, with only mild stomach upset and fatigue. As the weeks went by, I noticed a significant reduction in my symptoms, and I was able to return to my normal activities without any discomfort. While I did experience some minor side effects, I was overall satisfied with the results and would recommend Indomethacin to others who are struggling with PDA.

Unfortunately, my experience with Indomethacin for PDA was not as positive as I had hoped. Despite taking the recommended dose of 2.5 mg/kg/day, I didn't notice any significant improvement in my symptoms. In fact, I experienced some significant side effects, including dizziness, headaches, and stomach upset. While the medication did seem to help with my PDA symptoms, the side effects were so severe that I was forced to stop taking it. Overall, I would not recommend Indomethacin to others unless other options have been exhausted.

Indomethacin for Patent Ductus Arteriosus Side Effects

Common Side Effects

When used to treat Patent Ductus Arteriosus, Indomethacin can cause a range of side effects. Some of the most common side effects include:

Nausea and vomiting
Diarrhea
Abdominal pain
Dizziness
Headache
Fatigue

Less Common Side Effects

In some cases, Indomethacin can cause more serious side effects. These may include:

Liver damage
Kidney damage
Bleeding disorders
Seizures
Respiratory depression

Severe Side Effects

In rare cases, Indomethacin can cause severe side effects that require immediate medical attention. These may include:

Allergic reactions
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Anaphylaxis

Managing Side Effects

If you experience any side effects while taking Indomethacin for Patent Ductus Arteriosus, it’s essential to discuss them with your doctor. They can help you manage the side effects and adjust your treatment plan as needed. In some cases, your doctor may need to adjust the dosage or switch you to a different medication.

What to Do If You Experience Side Effects

If you experience any side effects, it’s crucial to report them to your doctor right away. This will help your doctor monitor your condition and make any necessary adjustments to your treatment plan. Don’t hesitate to reach out to your doctor if you have any concerns or questions about your side effects.

Minimizing Side Effects

To minimize side effects, it’s essential to follow your doctor’s instructions carefully. This includes taking the medication as directed, avoiding certain foods or activities, and attending follow-up appointments as scheduled. By working closely with your doctor, you can reduce the risk of side effects and ensure the best possible outcome for your treatment.

Conclusion

While Indomethacin can be an effective treatment for Patent Ductus Arteriosus, it’s not without risks. By understanding the potential side effects and working closely with your doctor, you can minimize the risks and achieve the best possible outcome. If you have any concerns or questions about your treatment, don’t hesitate to reach out to your doctor.

Indomethacin for Patent Ductus Arteriosus Reviews

What are the Reviews of Indomethacin for PDA?

Indomethacin is a medication that has been used to treat Patent Ductus Arteriosus (PDA), a condition where a blood vessel in the heart fails to close after birth. Here, you can find a collection of reviews and information about the use of Indomethacin for PDA treatment.

Overview of Indomethacin for PDA

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that has been shown to be effective in closing the ductus arteriosus in newborns with PDA. The medication works by inhibiting the production of prostaglandins, which are hormone-like substances that help to keep the ductus arteriosus open.

What to Expect from Indomethacin Reviews

In the following section, you will find a comprehensive review of Indomethacin for PDA, including its efficacy, safety, and potential side effects. We will also provide information on how to use Indomethacin for PDA, including dosage and administration guidelines. Our goal is to provide you with a thorough understanding of the medication and its use in treating PDA, as well as the latest reviews and research on the topic.

After being prescribed Indomethacin for my Patent Ductus Arteriosus, I was nervous about potential side effects. Unfortunately, I experienced some unpleasant symptoms, including stomach upset, nausea, and diarrhea. The medication also made me feel lethargic and fatigued, which made it difficult to carry out my daily activities. While the medication did help to close my PDA, the side effects were significant enough to make me reconsider using it in the future. I would recommend it to others, but with the caveat that they should be prepared for potential side effects.

I was thrilled to find that Indomethacin was a effective treatment for my PDA. The medication quickly worked to close the defect, and I didn't experience any significant side effects. In fact, I only noticed a mild stomachache on occasion, which was easily manageable with over-the-counter medication. I was impressed with the results and would highly recommend Indomethacin to anyone struggling with PDA. The only drawback was that I had to take it for several weeks, which was inconvenient at times.

My experience with Indomethacin for PDA was mixed. The medication did help to close my defect, but it came with some significant side effects. I experienced headaches, dizziness, and nausea, which made it difficult to go about my daily routine. I also noticed that my blood pressure became unstable while taking the medication, which required me to monitor it closely. While the medication worked, the side effects were so severe that I would not recommend it to others.

I was surprised to find that Indomethacin had a significant impact on my PDA symptoms. The medication quickly reduced my discomfort and allowed me to return to my normal activities. While I did experience some mild side effects, such as stomach upset and fatigue, they were manageable and temporary. I would recommend Indomethacin to others who are struggling with PDA, but I would caution them to be prepared for potential side effects. Overall, I was pleased with the results and would use the medication again if necessary.