Both Zyrtec-D and Bupropion offer similar effectiveness, with differences in speed and duration of relief.

Zyrtec-D has fewer side effects and is less likely to interact with other medications.

Both drugs are low-risk for addiction when used properly, with minimal potential for misuse.

Zyrtec-D has a simple once-daily dose, making it easier to stick to a treatment routine.

Both drugs have some contraindications depending on individual health conditions, but neither has major restrictions.

Zyrtec-D is ideal for fast relief, ease of use, and lower addiction risk, making it best for acute symptoms.