Both Tylenol PM and Duloxetine offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Both Tylenol PM and Duloxetine have similar safety profiles, with mild and transient side effects. Neither presents significant long-term safety concerns.

Both Tylenol PM and Duloxetine have a low risk of addiction when used correctly under medical supervision, with minimal potential for misuse.

Tylenol PM offers the convenience of a once-daily dose, simplifying treatment adherence for patients.

Both Tylenol PM and Duloxetine have some contraindications based on individual health conditions, but neither has significantly more restrictions than the other.

Tylenol PM is ideal for patients needing quick relief and higher potency. It’s easier to use, safer for most patients, and has a lower addiction risk, making it a top choice for acute symptoms.