Both Trazodone and Lithium offer similar effectiveness, with differences in speed and duration of relief.

Both drugs have comparable safety profiles, with mild side effects that are generally well-tolerated.

Both drugs are low-risk for addiction when used properly, with minimal potential for misuse.

Trazodone has a simple once-daily dose, making it easier to stick to a treatment routine.

Lithium is safer for patients with cardiovascular issues or diabetes.

Both drugs are good options depending on the patient’s needs, with Trazodone better for quick relief and Lithium for long-term management.