Both Sudafed PE and Hydroxyzine offer similar effectiveness, with differences in speed and duration of relief.

Sudafed PE has fewer side effects and is less likely to interact with other medications.

Both drugs are low-risk for addiction when used properly, with minimal potential for misuse.

Both drugs are easy to use, with clear dosing schedules to ensure treatment adherence.

Sudafed PE has fewer contraindications, making it suitable for patients with multiple health conditions.

Both drugs are good options depending on the patient’s needs, with Sudafed PE better for quick relief and Hydroxyzine for long-term management.