Both Stiolto Respimat and Horizant offer similar effectiveness, with differences in speed and duration of relief.

Both drugs have comparable safety profiles, with mild side effects that are generally well-tolerated.

Horizant has a more stable effect and is less likely to lead to addiction over time.

Stiolto Respimat has a simple once-daily dose, making it easier to stick to a treatment routine.

Both drugs have some contraindications depending on individual health conditions, but neither has major restrictions.

Stiolto Respimat is ideal for fast relief, ease of use, and lower addiction risk, making it best for acute symptoms.