Both Niacin and Caffeine offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Both Niacin and Caffeine have similar safety profiles, with mild and transient side effects. Neither presents significant long-term safety concerns.

Caffeine has a more stable therapeutic effect and is less likely to lead to dependency or cravings compared to Niacin.

Both Niacin and Caffeine are easy to use, with straightforward dosing regimens that ensure good adherence.

Niacin has fewer contraindications, making it suitable for a broader range of patients, including those with comorbidities.

Both drugs offer advantages depending on treatment goals. Niacin is great for fast relief, while Caffeine is better for long-term management. The choice depends on the patient’s specific needs.