Both Mirtazapine and Fluoxetine offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Fluoxetine is gentler on the liver and kidneys and has a better safety profile for long-term use, particularly for older patients or those with pre-existing conditions.

Fluoxetine has a more stable therapeutic effect and is less likely to lead to dependency or cravings compared to Mirtazapine.

Fluoxetine offers greater flexibility with different delivery forms, making it suitable for patients with specific preferences or medical needs.

Fluoxetine is better for patients with cardiovascular or diabetes-related issues, as it has fewer interactions with other medications.

Fluoxetine is better suited for chronic conditions, offering longer-lasting effects and a favorable safety profile for long-term use. Its flexibility in administration makes it a strong option for various patient needs.