Both Metolazone and Zanaflex offer similar effectiveness, with differences in speed and duration of relief.

Both drugs have comparable safety profiles, with mild side effects that are generally well-tolerated.

Both drugs are low-risk for addiction when used properly, with minimal potential for misuse.

Zanaflex offers various forms, including liquid and injectable options, providing more flexibility.

Zanaflex is safer for patients with cardiovascular issues or diabetes.

Zanaflex is better for chronic conditions, offering longer-lasting effects and more flexibility.