Both Lisdexamfetamine and Guanfacine offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Guanfacine is gentler on the liver and kidneys and has a better safety profile for long-term use, particularly for older patients or those with pre-existing conditions.

Lisdexamfetamine has a lower risk of dependency, making it a safer option for patients concerned about addiction.

Lisdexamfetamine offers the convenience of a once-daily dose, simplifying treatment adherence for patients.

Lisdexamfetamine has fewer contraindications, making it suitable for a broader range of patients, including those with comorbidities.

Lisdexamfetamine is ideal for patients needing quick relief and higher potency. It’s easier to use, safer for most patients, and has a lower addiction risk, making it a top choice for acute symptoms.