Both Isotretinoin and Ketamine offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Both Isotretinoin and Ketamine have similar safety profiles, with mild and transient side effects. Neither presents significant long-term safety concerns.

Ketamine has a more stable therapeutic effect and is less likely to lead to dependency or cravings compared to Isotretinoin.

Both Isotretinoin and Ketamine are easy to use, with straightforward dosing regimens that ensure good adherence.

Both Isotretinoin and Ketamine have some contraindications based on individual health conditions, but neither has significantly more restrictions than the other.

Both drugs offer advantages depending on treatment goals. Isotretinoin is great for fast relief, while Ketamine is better for long-term management. The choice depends on the patient’s specific needs.