Both Hydroxyurea and Prednisone offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Both Hydroxyurea and Prednisone have similar safety profiles, with mild and transient side effects. Neither presents significant long-term safety concerns.

Prednisone has a more stable therapeutic effect and is less likely to lead to dependency or cravings compared to Hydroxyurea.

Both Hydroxyurea and Prednisone are easy to use, with straightforward dosing regimens that ensure good adherence.

Prednisone is better for patients with cardiovascular or diabetes-related issues, as it has fewer interactions with other medications.

Both drugs offer advantages depending on treatment goals. Hydroxyurea is great for fast relief, while Prednisone is better for long-term management. The choice depends on the patient’s specific needs.