Both Guaifenesin and Sudafed offer similar effectiveness, with differences in speed and duration of relief.

Guaifenesin has fewer side effects and is less likely to interact with other medications.

Sudafed has a more stable effect and is less likely to lead to addiction over time.

Both drugs are easy to use, with clear dosing schedules to ensure treatment adherence.

Guaifenesin has fewer contraindications, making it suitable for patients with multiple health conditions.

Both drugs are good options depending on the patient’s needs, with Guaifenesin better for quick relief and Sudafed for long-term management.