Both Guaifenesin and Montelukast offer similar effectiveness in symptom control, with the main difference being how quickly they act. Either drug is a viable option depending on the patient’s needs.

Both Guaifenesin and Montelukast have similar safety profiles, with mild and transient side effects. Neither presents significant long-term safety concerns.

Both Guaifenesin and Montelukast have a low risk of addiction when used correctly under medical supervision, with minimal potential for misuse.

Both Guaifenesin and Montelukast are easy to use, with straightforward dosing regimens that ensure good adherence.

Guaifenesin has fewer contraindications, making it suitable for a broader range of patients, including those with comorbidities.

Both drugs offer advantages depending on treatment goals. Guaifenesin is great for fast relief, while Montelukast is better for long-term management. The choice depends on the patient’s specific needs.