Both Guaifenesin and Orilissa offer similar effectiveness, with differences in speed and duration of relief.

Guaifenesin has fewer side effects and is less likely to interact with other medications.

Both drugs are low-risk for addiction when used properly, with minimal potential for misuse.

Both drugs are easy to use, with clear dosing schedules to ensure treatment adherence.

Guaifenesin has fewer contraindications, making it suitable for patients with multiple health conditions.

Both drugs are good options depending on the patient’s needs, with Guaifenesin better for quick relief and Orilissa for long-term management.